See below Essay Example | Topics and Well Written Essays - 1000 words

See below - Essay Example The capillaries play an important role in healing a wound. The four overlapping phases are used to explain the healing process. This is a systematic phenomenon. The four phases include homeostasis, inflammation, proliferation, and maturation. Homeostasis is a process which involves the platelets to form clots. Furthermore, the inflammatory cells deride injured tissue during the inflammatory phase. Epithelialization, fibroplasia, and angiogenesis occur during the proliferative phase (Romo III, n.d). The hemorrhage caused by disruption in the blood vessels is controlled by clot formation which contains fibrin mesh with aggregated platelets embedded in it. Fibrin is the end product of coagulation pathway which causes homeostasis to take place. It provides a scaffold for the migration of inflammatory and mesenchymal cells (Wound Healing, n.d). Platelet aggregation leads to release of cytokines. These cytokines influence wound healing either directly or indirectly. The processes of clot f ormation and platelet aggregation halt when stimuli for clot formation fritter away. Lysis of clot starts along with clot formation and is mediated by plasminogen activator. This activator converts plasminogen to plasmin (Wound Healing, n.d). The second phase is called inflammation. It starts when the tissue trauma stimulates the inflammatory response. â€Å"Immediately after injury intense local vasoconstriction occurs, mediated by circulating catecholeamines and prostaglandins released by injured cells. This is followed by vasodilatation and increased capillary permeability resulting in local edema. This is mediated by histamine, kinins, prostaglandins, leukotrienes, and endothelial cell products† (Wound Healing, n.d). The tissue does not observe presence of any leukocytes as yet. The wounded tissues contain neutrophils which hare the first leukocytes to appear in the wounded tissues. They phagocytose damaged tissue or bacteria. Neutrophils themselves are phagocytosed by ma crophages (Wound Healing, n.d). There are a few symptoms observed when the wound is healing because of the physiological changes. The pH change is observed because of the breakdown of tissues and bacteria which also causes pain. This also results in swelling and decreased tissue oxygenation due to disruption of blood vessels (Wound Healing n.d). Furthermore, the white blood cells namely monocytes and lymphocytes start performing their functions in the healing process. Monocytes turn into macrophages when these white blood cells migrate from capillaries into extra vascular space. Macrocytes phagocytose bacteria and tissue debris and secrete enzymes called collagenase and elastase, which are responsible for breaking down damaged matrix (Wound Healing, n.d). Lymphocytes produce various factors like HB-EGF (Heparin binding epidermal growth factor) and basic fibroblast growth factor. Adding on to this, they are also involved in cellular and humoral immunity. Neutrophilis dominate for the initial 24-48 but 48-72 hours later they are outnumbered by macrophages which persist for a few days. However, after 5-7 days fibroblasts are the principal cell type (Wound Healing, n.d). The third phase called proliferation constitutes epithelialization, fibroplasias and angiogenesis. Epithelialization is the â€Å"process of covering a denuded surface with epithelium† (Medical Dictionary, n.d). Fibroplasia is another part of the proliferative phase. It

Marketing Theory Term Paper Example | Topics and Well Written Essays - 2000 words

Marketing Theory - Term Paper Example Keeping in mind the concept of marketing theories and techniques, the establishment and operation of a new business venture would be discussed. The new business venture selected for this study is a book store. 1.2 Business Idea: Book Store The new business idea that has been considered for this study is a book store that would be set in California. The name of the book store would be â€Å"Book Worm†. However, setting up a business requires following the marketing theories and utilizing the strategies. In this section of the study, specification related to the new venture has been stated. 1.2.1 Mission and Objectives Book Worm’s mission is to offer quality books at the lowest possible price to the customers in California. The company would additionally allow customers to exchange old books and projects or assignments for their requirement (books, CDs and magazines). In order to attain this mission of the company, the objective of Book Worm would be: To offer hassle free purchase of new as well as second hand books, assignments and magazines at an affordable cost. To offer the students every university books and reading materials those are important to them at least possible price To offer online shopping experience to the customers along with the store To offer home delivery of products ordered within a specific area To attend break even in business within an year of commencing business To generate positive revenue at least after 4-6 months of inception To gain considerable amount of goodwill in comparison to the other competitors in the market (Ahmed 30-43). 1.2.2 Products and Services Book Worm will offer products as well as services. The products will range from text books (new as well as second-hand) for purchase, class notes, text books, audio book CDs on rent, etc. The text books available would include fiction and non-fiction books, subjects like business, physics, accounting, management, marketing, engineering and many more would be availa ble. These products would be available through the store of Book Worm. However, services like information regarding textbooks or class notes for rent or sale, web links for assignments, or solved assignments would be available for sale on the website of Book Worm. Book Worm would be offering a wholesome academic assistance to the students (Barkema and Vermeulen 7-26). 1.2.3 Suppliers Suppliers have a major role to play in the marketing environment because they are one of the integral players in the supply chain. Book Worm would be selecting the book wholesalers in California to avail the books for the customers. The second hand books or old class notes and assignment can be procured from the students, so they will play the role of suppliers in this case. However, as the business grows in terms of size and revenue, Book Worm can also directly procure books from the publishers and their stockists (Belin and Pham 44-50). II: MARKET ANALYSIS This section of the study plays a major role in the discussion of marketing theory because